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An important study appeared in JAMA Psychiatry in June 2016, providing additional evidence that high blood levels of vitamin B12 can slow the shrinking of the brain that commonly occurs after age 60. Previous studies have shown that vitamin B12 and other B vitamins (folic acid and vitamin B6) can slow the rate of brain atrophy in older subjects with mild cognitive impairment and decrease the risk of progression to Alzheimer’s disease. Overall, the emerging scientific evidence suggests if you can slow or prevent the shrinking of the brain, which is Common after age 60, you may decrease your risk of dementia and Alzheimer’s disease quite substantially. The latest study presented data from the Swedish National Study on Aging and Care

The study followed 501 subjects, ages 60 years and older, from 2001-2009. All subjects were free of dementia at the beginning of study. MRI imaging of their brains was conducted in 299 of the subjects routinely during the six-year follow-up period. Results showed individuals with higher blood levels of vitamin B12 showed a significant decrease in the rate of total brain tissue volume loss (atrophy) compared to individuals with lower blood levels of B12.

Understanding the B12 /Homocysteine Connection

Vitamin B12 is required to make a number of brain neurotransmitters and has been shown to have neuroprotective effects, which may directly slow brain shrinking. It also lowers a chemical in the blood called homocysteine. High homocysteine is known to be extremely damaging to the brain and cerebrovascular blood vessels, and high blood levels of homocysteine are strongly correlated with brain atrophy and risk of Alzheimer’s disease in many studies. In the JAMA Psychiatry study, higher homocysteine also was linked to more rapid brain volume shrinkage. So, there are at least two ways by which vitamin B12 may slow brain shrinking – by directly preventing loss of brain cells and by lowering homocysteine blood levels. What’s more, study participants with lower vitamin B12 levels and/or high homocysteine levels also showed increased white matter hyperintensity

(WMI) on their MRI scans, which is strongly tied to increased risk for cognitive decline and other mental health disorders.


Why Preventing Brain Shrinkage Matters

These studies are important because we know mild cognitive impairment (MCI) is the step that precedes development of Alzheimer’s disease. 1 We also know people older than age 60 who do not have MCI still have a brain shrinkage rate of 0.5 percent a year; while people with MCI have a brain shrinkage rate of 1 percent – double that of someone with no cognitive decline. Alzheimer’s patients show an average brain shrinkage of 2.5 percent per year. Thus, anything that slows brain shrinkage is considered to be an invaluable way to preserve cognition as we age.

Other B Vitamins Matter

This brings us to the Oxford Project to Investigate Memory and Aging (OPTIMA study and VITACOG study), for which researchers recruited 172 individuals older than age 70 who already had MCI. They gave half the subjects folic acid (800 mcg), vitamin B12 (500 mcg) and vitamin B6 (20 mg) per day for two years; the other half received a placebo pill. B-vitamin supplementation slowed brain atrophy by 30 percent, on average, and in some cases up to 53 percent. Cognitive tests showed that the greater the rate of brain atrophy, the more rapid the decline in cognitive function.2

This article was originally published on the Dynamic Chiropractic Website. It was written by James P. Meschino, DC, MS.



References

  1. Hooshmand B, et al. Association of vitamin B12, folate, and sulfur amino acids with brain magnetic resonance imaging measures in older adults: a longitudinal population-based study. JAMA Psychiatry, June 2016;73(6).
  2. Smith AD, et al. Homocysteinelowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial. PLOS One, September 2010;5(9):e12244.

 



By Ada Boneth 26 Sep, 2023
How many times have you gone to your medical doctor and been told…”In order to get better, you’re going to have to find a way to reset your nervous system so that it recoups from the stress of regular life.” Most likely…never! At most, doctors will say, “Of course stress affects your health”, as they write you a prescription for a drug. Now contrast that to a good chiropractor or other alternative health care practitioner, and you probably have been asked that question and given more natural treatments, like a great adjustment, and other recommendations to assist you with that. But what else can YOU do? Dr. Mark Hyman, one of the world’s leading Functional Medicine Doctors and 10 times New York Times Best-Selling Author, has a different opinion that is more in alignment with how I approach the human body and help it restore health and healing. As he says, “There are three things that are critical for healing: it’s what you eat, moving your body, and learning how to reset your nervous system.” And what does he recommend for resetting your nervous system…? He recommends “Tapping”, and says that “Tapping is one of the most directed and powerful ways to peel those layers away of chronic stress. It’s very effective for very difficult problems.” If you want to learn about how you can overcome illness, create long-term, lasting health, or just get over regular stress and feel better, then I highly recommend you consider “Tapping”, also called EFT. EFT or Emotional Freedom Technique was discovered well over a decade ago, and there is lots of data about it available on the web. I suggest this link for a good short explanation of Tapping and how to do it:
By Ada Boneth 26 Sep, 2023
New Hampshire Study Concludes That Patients Who Receive Chiropractic Care are 55% Less Likely to Require Opioid Prescriptions. OBJECTIVE: Pain relief resulting from services delivered by doctors of chiropractic may allow patients to use lower or less frequent doses of opioids, leading to the reduced risk of adverse effects. The objective of this investigation was to evaluate the association between the utilization of chiropractic services and the use of prescription opioid medications.
By Ada Boneth 26 Sep, 2023
Opioids Misuse and Addiction: How Chiropractic Can Help Thirty-five-year-old Megan presented with chronic neck and upper back pain. Megan’s pain began four years earlier, following a car accident where she injured her cervical spine and upper thoracic spine. The pain became a daily part of Megan’s routine. When she became pregnant with her first child, she was taking opioid pain medication daily, but she was able to stop during the first trimester. After her first pregnancy, Megan continued to have pain and began to retake opioids. Pregnant with her second child, Megan struggled to stop the medication. Seeking help, she found support from her husband, family and friends. However, the pain continued to rule her life, making stopping difficult. The treatment of chiropractic care—or any other complementary therapy—was never provided as an option to Megan for her chronic neck and back pain. Chronic Pain Is a Widespread Problem Megan’s story is not an unfamiliar one. News stories about the opioid addiction abound. It is a major problem throughout the U.S., and it does not discriminate. We live in a society that is in pain. According to the American Academy of Pain Management, 100 million Americans suffer from chronic pain. 1 In addition to the reports of chronic pain, opioid medications have been overprescribed. Intended for pain associated with cancer and the end stages of life, opioids are less effective in treating noncancerous, chronic pain. 2,3 The opioid crisis is not new. Its usage in the U.S. can be traced back to the late 1800s when morphine and heroin became readily available. During that time, the most commonly addicted were white females. In the early 1900s, opioids, such as heroin, were used as cough suppressants, and not much was known about the drug’s long-term effects. As usage became widespread, it became apparent that opioids were addictive. In 1914, the Harrison Narcotics Act was initiated, and a tax was imposed on anyone making, selling or importing any type of opium. In 1924, heroin became illegal. 4 In the 1980s, published articles attested to the safety of long-term heroin usage. An escalation of usage began, resulting in a significant impact on the country. A wide variety of opioids can be prescribed within the following categories: Natural Opioids like morphine, which is derived from the poppy plant Semi-synthetic like hydrocodone and heroin Fully synthetic-like tramadol or fentany l When opioid prescriptions are no longer available, many individuals begin using heroin due to its low cost and ready availability. 5 Prescription rates vary across the country. The highest overdose rates are found in West Virginia, New Mexico, New Hampshire, Kentucky, and Ohio. 6 Women are twice as likely to use prescription opioids as their male counterparts, and they tend to be between the ages of 25-54. A correlation between deaths due to opioid misuse and benzodiazepines has been found. 7 Many patients are simultaneously prescribed both drugs. One study found that women have been prescribed opioids for low back and pelvic pain during pregnancy even though the long-term effects were well known. 8 The prevalence of low back pain and pelvic pain is common and ranges between 68 and 72 percent of pregnant women. 9, 10 For chronic pain in pregnancy, the American Pain Society guidelines 11 suggested that women be counseled regarding the risks and benefits of opioid therapy, with the recommendation that there should be little to no use during pregnancy. The American College of Obstetricians and Gynecologists makes numerous recommendations to minimize opioid use and highlight nonpharmacological options for chronic pain. 12 For those who are addicted, abrupt discontinuation of opioids during pregnancy can lead to preterm labor, fetal demise, or fetal distress. Opioid agonist therapy with methadone or buprenorphine is the standard recommendation. Infants exposed to opioid use may develop neonatal abstinence syndrome (NAS), which was first described in the clinical literature in the 1970s. In 2012 alone, 21,000 infants were diagnosed, a five-fold increase from the previous 12 years. There is a high correlation between opioid exposure and death from birth to five years of age. 13, 14 Opioid exposure tends to be accidental, such as a child accidentally ingesting a pill or being stuck by a heroin needle. Since infants and small children have a low body mass, even a small amount of exposure can have long-term and damaging effects. Exposure tends to decline before it starts to elevate beginning at age 12 and increasing until ages17-18, where it plateaus. Opioid use in adolescents is much different than in the younger counterparts, as it tends to result from leftover prescriptions found in medicine cabinets. 13, 14 The Role of Chiropractic Chiropractic can often help with chronic pain as an alternative to medications. Typically, after a regimen of chiropractic treatment, patients are able to reduce or eliminate unnecessary medications. Also, we can frequently help patients avoid unnecessary surgeries. Our community has drug drop boxes for opioid disposal, drug take-back programs, and testing programs. Also drug lock boxes are available. Check with your local pharmacist and city hall. References 1 Institute of Medicine Report from the Committee on Advancing Pain Research, Care, and Education: Relieving Pain in America, A Blueprint for Transforming Prevention, Care, Education and Research. The National Academies Press, 2011. 2 Trescot AM, Glaser SE, Hansen H, Benyamin R, Patel S, Manchikanti L. Effectiveness of Opioids in the Treatment of Non-Cancer Pain. Pain Physician. 2008; 11. 181-200. 3 Chou R, Deyo R. Devine B. The Effectiveness and Risks of Long Term Opioid Treatment in Chronic Pain. Agency for Healthcare Research and Quality. September 2014 4 Kolodny A, Courtwright D, Hwang C, Kreiner P, Eadie J, Clark T, Alexander G. The Prescription Opioid and Heroin Crisis: A Public Health Approach to an Epidemic of Addiction. Annual Review of Public Health. Vol 36 (2015) pp559-574 5 Jones CM. Heroin use and heroin use risk behaviors among nonmedical users of prescription opioid pain relievers – United States, 2002-2004 and 2008-2010. Drug Alcohol Depend. 2013;132(1-2):95-100. 6 CDC https://www.cdc.gov/vitalsigns/opioid-prescribing/ 7 American Society of Addiction Medicine. Opioid Addiction Fast Facts(2016) https://www.asam.org/docs/default-source/advocacy/opioid-addiction-disease-facts-figures.pdf 8 Maeda A, Bateman BT, Clancy CR, Creanga AA, Leffert LR. Opioid Abuse and Dependance During Pregnancy: Temporal Trends and Obstetrical Outcomes. Anesthesiology 2014. Dec;121 (6):1158-65 9 Wang SM, Dezinno P, Maranets I, Berman MR, Caldwell-Andrews AA, Kain ZN. Low back pain during pregnancy: prevalence, risk factors, and outcomes. Obstet Gynecol 2004;104(1):65–70 10 Mogren IM, Pohjanen AI. Low back pain and pelvic pain during pregnancy: prevalence and risk factors. Spine 2005;30(8):983–991 11 American Pain Society Guidelines:Guideline for the Use of Chronic Opioid Therapy in Noncancer Pain: Evidence Review: http://americanpainsociety.org/uploads/education/guidelines/chronic-opioid-therapy-cncp.pdf 12 Committee on Obstetric Practice American Society of Addiction Medicine August 2017: American College of Obstetricians and Gynecologists https://www.acog.org/Resources-And-Publications/Committee-Opinions/Committee-on-Obstetric-Practice/Opioid-Use-and-Opioid-Use-Disorder-in-Pregnancy 13 Patrick S and Schiff D. A Public Health Response to Opioid Use During Pregnancy. American Academy of Pediatrics. Pediatrics. Vol 139/Issue 3 (2017) 14 Allen J, Marcel C, Spiller H, Thiphalak C, Hodges N, Smith G. Prescription Opioid Exposures Among Children and Adolescents in the United States: 2000-2015. Pediatrics. Vol 139. No 4(2017)
By Ada Boneth 25 Jul, 2023
The sciatic nerves are the largest and longest nerves of the body, reaching about the size of your thumb in diameter, and running down the back of each leg. When these nerves are irritated or affected by the inflammation of nearby soft tissues, doctors refer to this as sciatica
By Ada Boneth 25 Jul, 2023
Not sure if you are sitting efficiently and appropriately at your computer desk? Watch this video and make adjustments as needed!
By Ada Boneth 25 Jul, 2023
Below is a link to mental health resources in San Mateo County from Melissa Platte. Melissa is a fellow member of my San Mateo Rotary club and the director of San Mateo nonprofit mental health agencies. www.smccontractors.org
By Ada Boneth 25 Jul, 2023
Something Simple to Give Your Immune System A Boost Here’s the link. Once you’ve gotten the hang of it, it’s pretty quick, just a few minutes, to do a daily drainage routine. If you feel under the weather, I suggest two times per day, morning and evening. Otherwise once per day is sufficient.
By September 3rd, 2021 30 May, 2023
According to the U.S. Geological Survey, approximately 71 percent of the earth’s surface is composed of water. Similarly, 60 to 70 percent of the average adult human body is composed of water. If you’re a 120-pound female, you’re made of at least 72 pounds, or 36 quarts, of water. If you’re a 175-pound male, you’re carrying around at least 105 pounds, or 52 to 53 quarts, of water. In either case, that’s a lot of liquid. But that water isn’t in your body for ballast. It’s there for work. Water provides the medium in which all our physiological processes take place. In other words, water makes our lives possible. This makes sense when we consider that the proportion of water on earth and in our bodies is approximately the same. Water is the conduit that makes things happen. From the perspective of complex biological organisms, without water there are no organs, no tissues, and no cells. And if there are no cells, there is no life. Thus, water is essential to our survival. But our internal supply of water is dynamic. We use up more or less water depending on our activities. Of course, being more physically active causes more water to be consumed in metabolic processes such as releasing energy from ATP adenosine triphosphate) molecules.1 Rebuilding ATP supplies requires water as well. Additionally, your kidneys maintain dynamic control over the amount of water in your blood as one of the primary means of regulating blood pH, which must be in a very narrow range of 7.35 to 7.45. Even minor deviations from optimal pH levels can result in symptoms such as fatigue, headache, increased heart rate, muscle pain, and jaundice. Maintaining sufficient water intake is as important a requirement for good health as is regular exercise, a healthy diet, and obtaining necessary rest. The question naturally arises, how much water should I drink each day? Drinking sufficient water takes a little bit of effort, but there is a big payoff. In fact, the recommendation to drink more water is possibly the most important nutritional advice one could receive. If one is not drinking enough water, any other nutritional improvements will have less of an impact. Specifically, take your body weight and divide it in half. That’s the number of ounces of fluid you need per day. You can use water, juice, soup, herbal teas, anything which is mostly fluid. Because they are “diuretics” or eliminate fluid from your body, alcohol and caffeinated beverages don’t count as part of your daily fluid. In fact you have to add fluid to make up for their deleterious effect. Example: I weigh 122 pounds. 122 x 1/2 = 61, i.e. I need 61 oz of fluid per day. If I have a cup of caffeinated coffee for breakfast, now I need 69 oz. of fluid today. If I have a glass of wine with dinner, then I need to add another 8 oz. To make up for it (78 total for today). Hikers and those living or working at altitude know that by the time you feel thirsty (or your mouth feels dry), it’s too late. (2,3) Over the past few months, I’ve noticed a lot more of my friends, patients and loved ones complaining about pain in their neck, back, and joints. And it makes sense… with everyone staying home, people just aren’t moving around as much these days. So…I did a little research and came up with a quick routine to help improve joint comfort and better mobility. It only takes about 30-seconds to do, but it will make a HUGE impact on how you feel all day long. All you need is an empty glass and the alarm on your phone. Every time you sit down — whether it’s to work, to watch a show, or to simply read through your emails — set an alarm for 30 minutes. When the timer goes off, walk to the kitchen and get a drink of water. DON’T just keep a glass of water next to you (I’ll tell you why in a second…) First, I’m going to explain WHY you’re getting water: Believe it or not, a lot of joint and back pain is actually due to dehydration . In-between each vertebra is a disk that acts as a cushion for your spine. The inner layers of these disks are filled with water…and when we bend our spines to sit, the disks compress and some of that water leaks out. This isn’t a problem if you’re properly hydrated; those disks will simply get refilled by your body. But if you don’t drink enough water, that won’t happen…and your vertebrae will be left grinding against each other, causing you an extreme amount of stiffness and pain. It’s estimated that roughly 70% of Americans don’t drink enough water — which means there’s a good chance you’re dehydrated without even knowing it. By reminding yourself to drink more water, you’ll decrease back pain and improve your overall health. So… Why not just keep a glass of water next to you? You won’t be surprised when I tell you: Humans just weren’t meant to sit around a house all day! As strange as it sounds, moving around is one of the best ways to decrease back and joint pain. In fact, a 2011 study conducted in Minneapolis showed that people who sit less also experience much less back and neck pain. Researchers challenged sedentary workers to stand up more frequently — reducing their sit-time by 66 minutes a day. After 7 weeks of this, participants reported 54% less back and neck pain. When it comes down to it, you and I weren’t designed to sit for more than 30 minutes at a time. When you sit down for hours and hours at time, it’s a recipe for back and joint pain. By setting an alarm and making yourself get up to drink a glass of water, you’ll give your body two of the most important tools it needs to keep your joints healthy and happy. 1. Graham MJ, et al: Low-Volume Intense Exercise Elicits Post-exercise Hypotension and Subsequent Hypervolemia, Irrespective of Which Limbs Are Exercised. Front Physiol 2016 May 31. doi: 10.3389/fphys.2016.00199 2. Thornton SM: Increased Hydration Can Be Associated with Weight Loss. Front Nutr 2016 Jun 10. doi: 10.3389/fnut.2016.00018 3. Johnson EC: Hormonal and Thirst Modulated Maintenance of Fluid Balance in Young Women with Different Levels of Habitual Fluid Consumption. Nutrients 2016 May 18. doi: 10.3390/nu8050302
By September 2nd, 2021 30 May, 2023
Not sure what to do with all those extra plastic bags? How about you make your own lumbar support pillow! It’s easy, environmentally friendly, and can save your back.
By Wednesday, September 1st, 2021 30 May, 2023
Recumbent stationary bikes provide an excellent way to condition, improve cardiovascular function, and burn fat. Even for people who have bulging or herniated discs, they are usually a safe form of exercise. When pedaling the legs should not have to be wider than the position they would normally be. The pedal at its highest point should come no higher than ½ inch below the front of the seat (use a level to determine the height). You can add a firm foam pad to lift your buttocks if necessary. It may put less strain on the hips, knees, and back to lift higher than ½ inch. When the foot is fully extended there should still be ideally 7 degree bend in the knees. (5 degrees is absolute minimum), or else undue strain will be placed on the knees. All American Fitness (in San Jose) has a smaller bike for shorter people (5′ 4” and shorter): Body Guard. Their products and service are excellent, so I highly recommend going there for your sports equipment needs. It’s crankcase is 2” less than Precor and Lifecycle (3.5”) which helps put less stress on a short person’s body.
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